Eliza Esdaile's daughter Louisa Green first married William Grant, a purser in the Royal Navy (December 1816). My great-grandfather wrote that William Grant died of yellow fever in Antigua. William Grant's will was proved 16 December 1822, but it doesn't say where he died. The Navy List shows William Grant to be the purser on the Pyramus in December 1821 and J Jones to be the purser by March 1822. Between December 1821 and March 1822 the Pyramus was indeed in the West Indies. While not proving anything, this google book deals specifically with the terrible outbreak of yellow fever on the Pyramus in 1822: The Medico-chirurgical review, Volume 6 by James Johnson.